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. 2019 Aug 1;151(9):1116–1134. doi: 10.1085/jgp.201912327

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© 2019 Sato et al.

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Figure 1. — BK, Ca_V1.2, TRPV4, and Ca_V1.3 channels organize in clusters in multiple cell types exhibiting an exponential cluster area distribution. Representative superresolution ground state depletion images of the cluster organization of endogenous BK (blue), Ca_V1.2 (green), and TRPV4 (red) channels in arterial myocytes, endogenous Ca_V1.2 (orange) channels in cardiomyocytes, endogenous Ca_V1.3 (light blue) channels in hippocampal neurons, and the two splicing variants Ca_V1.3_S (pink) and Ca_V1.3_L (yellow) expressed in tsA-201 cells. The plot summarizes the frequency distribution of the cluster areas for each channel. All the distributions were fit with a single exponential function. Average cluster areas and densities for each channel are presented in Table 2. TRPV4 data were modified from Tajada et al. (2017), Ca_V1.2 in cardiomyocytes was modified from Dixon et al. (2015), and Ca_V1.3 data were modified from Moreno et al. (2016).