Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 3;216(9):2113–2127. doi: 10.1084/jem.20181454

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 Prager et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — Serial killing of CD95KO targets. Serial killing activity of primary human NK cells was evaluated against CD95KO HeLa-CD48-NES-ELQTD-GFP-T2A-NES-VGPD-mCherry targets. Three independent experiments using IL-2–activated NK cells from three donors were conducted. A total of 60 NK cells were tracked over 15–17 h, and each of their killing events was characterized in terms of GrzB and Casp8 activity. (A) Diagram displaying the activity of GrzB and Casp8 in single killing events. Each row shows the killing sequence of one individual NK cell. (B) Relative distribution of reporter activity of all killing events for control and CD95KO HeLa targets. (C) Relative distribution of NK cells killing one to six different control or CD95KO HeLa targets.

HHS Vulnerability Disclosure