FIGURE 5.

Halonotius cobalamin synthesis gene clusters involved in cobalamin synthesis. The figure highlights the co-occurrence of cobalamin synthesis genes and their conserved order in the analyzed Halonotius genomes (n = 4). (A) Represents the genes from the first stage of the pathway, from uroporphyrinogen III to a,c-diamine. (B) Represents the genes from the second stage of the pathway, from a,c-diamine to vitamin B₁₂. The red star marks genes that are present in two copies. The genes depicted in white color were found not to be conserved in the gene cluster. The scale bar indicates gene lengths (in bp).