Table 2.
IC50 values (μg/mL) of PPSP, PPCP, and free PTX against MCF-7 and HepG2 cells after treatment for 24 and 48 h.
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MCF-7 | HepG2 | ||
---|---|---|---|---|
24 h | 48 h | 24 h | 48 h | |
PTX | 42.4 | 1.8 | 5,717.9 | 891.3 |
PPCP | 24.6 | 1.1 | 1,942.3 | 713.5 |
PPSP | 3.7 | 0.2 | 166.3 | 27.9 |
Ratioa (%) | 8.8 | 11.1 | 2.9 | 3.1 |
Ratiob (%) | 15.0 | 18.2 | 8.6 | 3.9 |
Percentage of PPSP micelle to free PTX,
Percentage of PPSP micelle to PPCP.