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. Author manuscript; available in PMC: 2019 Sep 3.
Published in final edited form as: Nat Methods. 2019 Jan 28;16(2):183–190. doi: 10.1038/s41592-018-0305-7

Fig. 3 |. Target cell trogocytosis is sufficiently sensitive to identify one cognate-antigen-expressing target cell from 10,000 non-antigen-expressing cells.

Fig. 3 |

a,b, Schematic and representative FACS plots for the mixture of cognate NYESO1-K562 target cells and noncognate A2-K562 cells (a) and the mixture of cognate MART1-K562 target cells to noncognate A2-K562 cells (b) co-incubated with either F5-Jurkat (top) or 1G4-Jurkat (bottom) cells. An overlay of the noncognate A2-K562 cells (gray) provides a clear comparison of trogocytosis in cognate versus noncognate K562 cells. Data are representative of three independent experiments.