Table 2.
Hospitalization Counts and Sex and Birth Year Adjusted Hospitalization Rates per 100 Person-Years for Survivors of Childhood and Adolescent Acute Lymphoblastic Leukemia from 5 to 10 Years Post-Diagnosis, Siblings, and a Population Sample.
| Survivors |
Siblings |
Population Sample |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N = 176 |
N = 232 |
N = 503 |
||||||||||
| Counts, Rates, and Confidence Intervals |
Counts, Rates, and Confidence Intervals |
Counts, Rates, and Confidence Intervals |
||||||||||
| Ct | PY | Rate | 95% CI | Ct | PY | Rate | 95% CI | Ct | PY | Rate | 95% CI | |
| Full Sample | 25 | 650.87 | 3.76 | 2.22, 6.36 | 30 | 1009.29 | 2.69 | 1.01, 7.18 | 35 | 1803.46 | 1.87 | 1.13, 3.09 |
| Demographic Characteristics | ||||||||||||
| Sex | ||||||||||||
| Male | 9 | 348.12 | 2.61 | 1.10, 6.19 | 15 | 511.75 | 3.66 | 1.19, 11.32 | 10 | 965.97 | 1.02 | 0.42, 2.46 |
| Female | 16 | 302.76 | 4.92 | 2.50, 9.70 | 15 | 497.54 | 2.54 | 1.11, 5.80 | 25 | 837.5 | 2.73 | 1.49, 5.01 |
| Ethnicity | ||||||||||||
| Not Hispanic | 23 | 570.04 | 3.97 | 2.28, 6.91 | 28 | 952.23 | 2.71 | 0.94, 7.84 | 28 | 1627.62 | 1.66 | 0.93, 2.97 |
| Hispanic | 2 | 80.83 | 1.79 | 0.27, 11.79 | 2 | 57.06 | 2.62 | 1.01, 6.78 | 7 | 175.84 | 3.5 | 1.52, 8.04 |
| Residential area | ||||||||||||
| Rural | 5 | 199.51 | 2.38 | 0.94, 6.02 | 16 | 352.75 | 4.72 | 0.93, 23.90 | 9 | 532.27 | 1.58 | 0.77, 3.27 |
| Urban | 20 | 451.36 | 4.32 | 2.34, 7.99 | 14 | 656.54 | 1.74 | 0.82, 3.71 | 26 | 1271.19 | 1.96 | 1.05, 3.66 |
| Clinical Factors | ||||||||||||
| Diagnosis year | ||||||||||||
| 1998 to 2003 | 8 | 393.38 | 1.87 | 0.67, 5.27 | 14 | 538.33 | 2.09 | 0.84, 5.18 | 24 | 1107.96 | 1.98 | 1.16, 3.36 |
| 2004 to 2008 | 17 | 257.49 | 6.69 | 3.95, 11.33 | 16 | 470.96 | 3.04 | 0.60, 15.32 | 11 | 695.5 | 1.55 | 0.58, 4.18 |
| Treatment | ||||||||||||
| BMT and/or radiation with chemotherapy | 1 | 63.85 | 1.54 | 0.18, 13.29 | 6 | 92.67 | 7.55 | 2.75, 20.75 | 3 | 190.01 | 1.56 | 0.28, 8.50 |
| Chemotherapy only | 24 | 587.03 | 3.9 | 2.23, 6.85 | 24 | 916.62 | 2.19 | 0.66, 7.25 | 32 | 1614.46 | 1.85 | 1.07, 3.21 |
| Risk group at diagnosis | ||||||||||||
| High risk and infants | 14 | 225.74 | 5.79 | 3.06, 10.95 | 15 | 336.21 | 4.18 | 1.93, 9.04 | 21 | 630.67 | 3.1 | 1.97, 4.90 |
| Standard risk | 11 | 425.13 | 2.77 | 1.16, 6.58 | 15 | 673.08 | 2.53 | 0.53, 12.00 | 14 | 1172.79 | 1.26 | 0.49, 3.25 |
| Age at diagnosis | ||||||||||||
| 0 to 5 years | 7 | 337.03 | 2.07 | 0.91, 4.73 | 17 | 566.61 | 4.16 | 1.21, 14.23 | 16 | 970.29 | 1.7 | 0.71, 4.07 |
| 6 to 22 years | 18 | 313.85 | 4.6 | 2.26, 9.37 | 13 | 442.68 | 1.97 | 0.91, 4.28 | 19 | 833.18 | 1.73 | 1.00, 3.01 |
Ct.: Total number of hospitalizations, more than 1 per person possible; PY: Person years; CI: Confidence Interval.