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. Author manuscript; available in PMC: 2019 Sep 3.
Published in final edited form as: Cell Rep. 2019 Apr 16;27(3):806–819.e5. doi: 10.1016/j.celrep.2019.03.066

Figure 3. Short Treatment of MEKis Alters T Cell Priming Ex Vivo.

Figure 3

(A) Schema of short treatment on Pmel-1 CD8+ T cells with human gp100 peptide pulse.

(B) Flow cytometry plots of CD44 and CD62L markers on CD8+ T cells after 5 days of priming.

(C) Frequency of CD44 CD62L subsets from CD8+ T cells by flow cytometry analysis. Average percentage of each subset is presented.

(D) Frequency of CD44+ CD62L cell population by flow cytometry.

(E) IFNγ production from supernatant at day 5 by cytokine profiling.

*p < 0.05; **p < 0.01; ***p < 0.001, Welch’s test. Error bars represent SD. Samples were biological replicates. The experiment was performed twice, and representative results are shown here.