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. Author manuscript; available in PMC: 2019 Sep 3.
Published in final edited form as: Biochem Biophys Res Commun. 1992 Nov 30;189(1):296–303. doi: 10.1016/0006-291x(92)91557-7

FIG. 4.

FIG. 4.

Ability of CCK receptor agonists and antagonists to inhibit binding of [125I]BH-CCK-8 to COS-7 cells expressing the human CCKB receptor. COS-7 cells were transfected with the mammalian expression vector, pCDL-SRα, containing the human CCKB receptor cDNA. Transfected COS-7 cells were incubated with either the tracer alone or increasing concentrations of agonists CCK-8 or gastrin-17-I (left panel) or antagonists L-365,260 and L-364,718 (right panel). Data are presented as percent saturable binding (total binding in the presence of labelled hormone alone minus binding in the presence of 1 μM CCK-8).