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. 2019 Jul 10;3(9):1235–1249. doi: 10.1002/hep4.1404

Table 1.

Correlations of Circulating EV Levels With Steatosis, Inflammation, and Fibrosis in All Male and Female FFC‐FED Mice With NASH

Macrophage EVs Neutrophil EVs Platelet EVs, Hepatocyte‐ASGR1+ EVs Hepatocyte‐CYP2E1+ EVs
r P r P r P r P r P
NAS (n = 36) 0.554 <0.001 0.511 0.001 0.406 0.014 0.432 0.024 0.428 0.012
Fat fraction (%) (n = 24) 0.158 0.405 0.622 <0.001 0.608 <0.001 0.266 0.163 0.100 0.997
Steatosis grade (n = 36) 0.364 0.029 0.197 0.249 0.206 0.228 0.486 0.032 0.525 0.013
Fibrosis stage (n = 36) 0.577 <0.001 0.597 <0.001 0.518 0.001 0.502 0.002 0.511 0.003
Lobular inflammation (n = 36) 0.415 0.012 0.341 0.042 0.205 0.231 0.463 0.010 0.425 0.016
Ballooning (n = 36) 0.502 0.002 0.650 <0.001 0.537 0.001 0.324 0.047 0.398 0.038