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. Author manuscript; available in PMC: 2019 Sep 3.
Published in final edited form as: Exp Hematol. 2018 Dec 25;70:31–41.e1. doi: 10.1016/j.exphem.2018.12.003

Figure 1: Multilineage engraftment of NHP cells in the MISTRG mouse model.

Figure 1:

(A) Gating strategy for the flow-cytometric assessment of NHP CD45+ cells (pCD45, 1st plot), granulocytes (CD11b+CD14−) vs. monocytes (CD11b+CD14+) (2nd plot), B cells (CD20+) vs. NK cells (CD16+) (3rd plot), and different T cell subsets (CD3+/CD4+/CD8+) (4th and 5th plot). (B) Representative gating for the assessment of NHP lineage subsets in the BM, PB, spleen and thymus of successfully engrafted MISTRG mice. (C) Representative gating strategy for the assessment and quantification of engrafted NHP CD34+ HSPC subpopulations in the BM of MISTRG mice.