Table 3.

Engraftment of NHP HSPCs in MISTRG mice

Freshly isolated and sort-purified NHP HSPCs were injected intrahepatic into neonatal MISTRG mice after sub-lethal irradiation (150 cGy). PB draws were performed every other week and the terminal endpoint for tissue harvest was performed 16–20 weeks post-transplant. Mice were counted as engrafted when showing a distinct population of NHP CD45⁺ cells >0.1% by flow-cytometry.