Table 2. The AF-VHD related signaling pathways regulated by combinatory miRNAs.

No.	The regulated signaling Pathways	Regulator	P
1	MAPK signaling pathway	Sub 1	0.0059
		Sub 2	0.0002
		Sub 4	0.0180
2	Wnt signaling pathway	Sub 1	0.0001
		Sub 2	0.0400
3	Focal adhesion	Sub 1	0.0008
		Sub 2	0.0011
4	ECM-receptor interaction	Sub 1	0.0220
		Sub 2	0.0140
5	Insulin signaling pathway	Sub 1	0.0025
		Sub 3	0.0220
6	p53 signaling pathway	Sub 1	0.0490
7	ErbB signaling pathway	Sub 1	0.0010
8	Phosphatidylinositol signaling system	Sub 1	0.0032
9	T cell receptor signaling pathway	Sub 1	0.0390
10	TGF-β signaling pathway	Sub 2	0.0490
11	Hypertrophic cardiomyopathy	Sub 2	0.0440
12	Jak-STAT signaling pathway	Sub 2	0.0460