Comparison 5. Length of ICU stay (log ratio of means scale).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Length of ICU stay (log units)	10		Mean Difference (IV, Random, 95% CI)	Subtotals only
1.1 Typical AP vs placebo	4	618	Mean Difference (IV, Random, 95% CI)	0.01 [‐0.11, 0.13]
1.2 Atypical AP vs placebo	4	577	Mean Difference (IV, Random, 95% CI)	‐0.09 [‐0.18, ‐0.00]
1.3 Statin vs placebo	1	272	Mean Difference (IV, Random, 95% CI)	0.06 [‐0.09, 0.21]
1.4 Alpha‐2 agonist vs placebo	1	71	Mean Difference (IV, Random, 95% CI)	‐0.22 [‐0.53, 0.08]
1.5 Cholinesterase inhibitor vs placebo	1	104	Mean Difference (IV, Random, 95% CI)	0.78 [0.46, 1.11]
1.6 Typical AP vs atypical AP	2	447	Mean Difference (IV, Random, 95% CI)	0.01 [‐0.13, 0.16]
1.7 Typical AP vs opioid	1	53	Mean Difference (IV, Random, 95% CI)	0.07 [‐0.24, 0.37]