Table 2.
Experimentally validated transcription factors that regulate the transcription of human GRINA by the RNA polymerase II (value: 0.0001), according to the TF2DNA database [82].
| Classification | TF | Description | References |
|---|---|---|---|
| Basic domain | ARNT2 | Aryl-hydrocarbon receptor nuclear translocator 2 | [84] |
| MYF6 | Myogenic factor 6 (Herculin) | [84] | |
| ID4 | Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | [85] | |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | [85] | |
| MESP1 | Mesoderm posterior bHLH transcription factor 1 | [85] | |
| c-MYC | Myc proto-oncogene | [86,87] | |
| Immunoglobulin fold | NFκB1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | [85,88] |
| Helix-turn-helix domain | HOXD8 | Homeobox D8 | [85] |
| EHF | ETS homologous factor | [84] | |
| PKNOX1 | PBX/knotted 1 homeobox 1 | [84] | |
| Zinc-coordinating DNA-binding domain | DMRT1 | Doublesex and mab-3 related transcription factor 1 | [89] |
| ZBTB6 | Zinc finger and BTB domain containing 6 | [88] | |
| ZBTB7C | Zinc finger and BTB domain containing 7C | [85] | |
| ESRRG | Estrogen-related receptor gamma | [84] | |
| MBD2 | Methyl-CpG binding domain protein 2 | [84] | |
| RORA | RAR-related orphan receptor A | [84] | |
| EGR3 | Early growth response 3 | [85] | |
| HINFP | Histone H4 transcription factor | [85] | |
| KLF13 | Kruppel-like factor 13 | [85] |