Figure 7.

(A) Schematics of the intratumor experiment through hydrogel injection. (B) Results of the intratumor injection in nude mice divided into four groups according to different injection treatments, including only injected saline (Blank), only injected Taxol solution (Tax·H₂O), injected Pluronic F127 hydrogel with Taxol (Tax·F127), and injected self-healing hydrogel based on glycol chitosan and DF-PEG with Taxol (Tax·CP) (the animal experiments were performed in accordance with protocols approved by the ethics committee of Cancer Hospital, Chinese Academy of Medical Science). (C) The volume and appearance of tumors in mice in the four groups. Reprinted with permission, as in Reference [81]. © 2017, Royal Society of Chemistry (London, UK). (D) Infrared thermal images for tumor-bearing mice under exposure to an AMF at different post-injection treatments (saline and DDMH) (the animal experiments were performed in accordance with protocols approved by the Laboratory Animal Research Center, Tsinghua University). (E) Tumor growth curves with different treatments (only saline, only DOX solution, DTX solution with PLGA nanoparticles, DOX solution with PLGA nanoparticles, and DDMH solution with AMF). (F1,F2) The temperature of different tumor sites shown during the exposure. Reprinted with permission [82]. © 2015, American Chemical Society (Washington, DC, USA).