Table 2.
Visual, topographic and functional outcomes for two different pulsed-light-accelerated CXL modalities at 12 months follow-up
| Baseline | Month 1 | Month 3 | Month 6 | Month 12 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| A-CXL (30*8) | A-CXL (45*5:20) | A-CXL (30*8) | A-CXL (45*5:20) | A-CXL (30*8) | A-CXL (45*5:20) | A-CXL (30*8) | A-CXL (45*5:20) | A-CXL (30*8) | A-CXL (45*5:20) | |
| UDVA (LogMAR) | 1.15±0.55 | 0.95±0.58 | 1.11±0.59 | 0.93±0.49 | 0.83±0.39 | 0.80±0.39 | 1.04±0.75 | 0.66±0.42† | 0.98±0.58 | 0.77±0.52† |
| CDVA (LogMAR) | 0.11±0.11 | 0.08±0.08 | 0.08±0.10 | 0.06±0.06 | 0.07±0.10 | 0.04±0.05 | 0.08±0.09† | 0.04±0.07† | 0.06±0.06† | 0.04±0.06† |
| SE (D) | 6.88±4.79 | 7.61±5.71 | 6.52±4.08 | 7.85±4.25 | 5.70±3.69 | 5.64±3.05† | 5.66±2.92† | 4.90±2.32† | 6.09±3.38† | 5.89±3.14† |
| Astigmatism (D) | 4.81±2.60 | 5.16±3.04 | 4.55±2.66 | 4.91±3.22 | 4.01±1.31† | 4.18±1.47† | 4.22±2.96† | 4.03±2.84† | 3.84±2.28† | 4.00±2.48† |
| Kmin (D) | 49.42±6.74 | 48.64±5.12 | 48.27±4.85 | 48.08±5.12† | 46.76±3.11 | 46.93±4.74 | 47.80±5.29† | 46.44±4.22† | 47.01±4.58† | 45.64±3.86† |
| Kmax (D) | 53.54±7.20 | 54.80±6.66 | 52.64±6.18 | 52.93±6.46† | 50.79±4.78 | 51.96±5.64† | 51.51±6.50† | 50.03±4.39† | 51.09±6.12† | 49.98±4.95† |
| Km (D) | 51.48±6.71 | 51.22±5.74 | 50.45±5.16 | 50.50±5.59† | 48.77±3.82 | 48.95±5.10† | 49.65±5.83† | 48.23±4.22† | 48.69±5.01† | 47.89±4.24† |
| CCT (μm) | 471.86±62.29 | 466.96±49.78 | 466.26±51.27† | 451.96±51.40† | 476.11±54.06† | 457.55±41.57 | 466.26±71.23† | 468.20±43.13 | 468.05±59.51 | 470.80±35.33 |
| TCT (μm) | 453.27±68.19 | 451.60±51.11 | 451.61±46.52† | 446.03±50.53† | 461.94±50.35† | 442.05±40.12 | 450.46±71.98 | 449.80±42.16 | 449.25±64.09 | 458.85±40.71 |
| ECD (cell/mm2) | 2594.18±368.28 | 2552.25±340.60 | 2494.55±432.27 | 2591.53±475.75 | 2539.60±261.70 | 2566.15±268.02 | 2562.33±230.70 | 2543.61±336.29 | ||
Note: †Significantly different compared with baseline measurement (Paired t-test, p<0.05).
Abbreviations: UDVA, uncorrected distance visual acuity; CDVA, corrected distance visual acuity; LogMAR, Logarithm of the Minimum Angle of Resolution; SE, spherical equivalent; Astigmatism, topographic astigmatism; Kmin, minimum keratometry; Kmax, maximum keratometry; Km, mean keratometry; CCT, central corneal thickness; TCT, thinnest corneal thickness; ECD, endothelial cell density (central).