Table 3. Subgroup analyses of HADS-A and SAS score in patients with or without anxiety at baseline (M0).
| Items | ICEP group | Control group | P value |
|---|---|---|---|
| Based on HADS-A score | |||
| Patients with anxiety at M0 (n, %) | 25 (25.5%) | 23 (23.5%) | |
| HADS-A score (M12) | 11.0±4.7 | 13.1±3.7 | 0.089 |
| HADS-A score change (M12-M0) | –1.1±2.1 | 1.1±1.9 | 0.001 |
| Anxiety (M12; n, %) | 20 (80.0%) | 22 (95.7%) | 0.230 |
| Patients without anxiety at M0 (n, %) | 73 (74.5%) | 75 (76.5%) | |
| HADS-A score (M12) | 4.3±2.5 | 4.5±2.1 | 0.748 |
| HADS-A score change (M12-M0) | 0.0±1.9 | 0.5±1.4 | 0.059 |
| Anxiety (M12; n, %) | 9 (12.3%) | 5 (6.7%) | 0.239 |
| Based on SAS score | |||
| Patients with anxiety at M0 (n, %) | 22 (22.4%) | 20 (20.4%) | |
| SAS score (M12) | 43.6±11.6 | 58.8±6.7 | <0.001 |
| SAS score change (M12-M0) | –12.8±9.3 | 1.3±7.7 | <0.001 |
| Anxiety (M12; n, %) | 7 (31.8%) | 16 (80.0%) | 0.002 |
| Patients without anxiety at M0 (n, %) | 76 (77.6%) | 78 (79.6%) | |
| SAS score (M12) | 38.0±7.5 | 39.0±8.2 | 0.445 |
| SAS score change (M12-M0) | –1.0±7.9 | 2.5±7.1 | 0.005 |
| Anxiety (M12; n, %) | 5 (6.6%) | 8 (10.3%) | 0.412 |
Data are reported as means±SD or count (percentage). A P value <0.05 was considered significant (t-test, chi-squared test, or Wilcoxon rank sum test). HADS-A: Hospital Anxiety and Depression Scale-Anxiety; SAS: Zung Self-rating Anxiety Scale; M: months; ICEP: Intensive Caregiver Education Program.