Table 2.
Associations between Plasmodium falciparum infection at antenatal enrolment and miscarriage/stillbirth, low birthweight, preterm birth and fetal growth restriction
Infection status | % (N/N total) | Adjusted odds ratio | 95% confidence interval | P |
---|---|---|---|---|
Miscarriage/stillbirtha (n = 2190) | ||||
No infection | 2.2 (44/1976) | |||
Submicroscopic infection | 1.8 (2/111) | 0.81 | (0.19, 3.41) | 0.77 |
Microscopic infection | 3.9 (4/103) | 1.96 | (0.68, 5.66) | 0.22 |
Low birthweightb (n = 1976) | ||||
No infection | 15.1 (270/1786) | |||
Submicroscopic infection | 14.3 (14/98) | 1.01 | (0.55, 1.84) | 0.98 |
Microscopic infection | 18.5 (17/92) | 0.97 | (0.54, 1.75) | 0.93 |
Preterm birthc (n = 1294) | ||||
No infection | 8.9 (105/1181) | |||
Submicroscopic infection | 1.7 (1/60) | 0.17 | (0.02, 1.26) | 0.08 |
Microscopic infection | 11.3 (6/53) | 1.22 | (0.49, 1.26) | 0.67 |
Small for gestational ageb (n = 1294) | ||||
No infection | 24.5 (289/1181) | |||
Submicroscopic infection | 33.3 (20/60) | 1.65 | (0.93, 2.92) | 0.09 |
Microscopic infection | 20.8 (11/53) | 0.71 | (0.35, 1.43) | 0.34 |
a Adjusted for treatment arm, gravidity, enrolment clinic, bed net use, undernutrition, stunting, ethnicity and socio-economic status
b Adjusted for treatment arm, gender of the baby, gravidity, number of study visits, enrolment clinic, bed net use, nutritional status, stunting, socio-economic status and timing of birthweight measurement
c Adjusted for treatment arm, gender of the baby, gravidity, number of study visits, enrolment clinic, bed net use, nutritional status, stunting, and socio-economic status