Table 3.
Areas exhibiting effects of drug, emotion, and drug×emotion interaction during Emotional Faces Matching Task at p<0.001, uncorrected, and cluster size of 20 voxels
Brain region | Laterality | Volume (voxels) | F-score | MNI coordinates |
||
---|---|---|---|---|---|---|
x | y | z | ||||
Drug main effect | ||||||
Lingual gyrus | L | 708 | 24.25 | −6 | −100 | −16 |
R | 631 | 13.41 | 24 | −106 | −2 | |
Emotion main effect | ||||||
Postcentral gyrus | L | 70 | 15.27 | −56 | −12 | 56 |
Lingual gyrus | L | 27 | 12.42 | −6 | −100 | −16 |
Superior temporal gyrus | R | 342 | 11.79 | 66 | 2 | −2 |
Insula | R | 107 | 10.19 | 52 | −22 | 14 |
Precentral gyrus | L | 33 | 10.14 | −34 | −20 | 74 |
R | 26 | 9.48 | 60 | 2 | 26 | |
Middle frontal gyrus | R | 82 | 9.9 | 40 | 8 | 30 |
R | 67 | 9.66 | 62 | 24 | 32 | |
Middle temporal gyrus | L | 20 | 8.15 | −66 | −10 | −6 |
Drug×Emotion interaction | ||||||
Middle orbitofrontal gyrus | R | 74 | 7.15 | 28 | 50 | −12 |
Superior frontal gyrus | L | 24 | 5.59 | −10 | 24 | 54 |
R right, L left