Table 1.
Bivariate and multivariable analyses of the continuous factors associated with fatigue as defined by a Fatigue Severity Scale score ≥4 in the Cohorte Lausannoise (CoLaus) study, Lausanne, Switzerland, 2014–2017
| Bivariate | Multivariable | |||||
| No fatigue | Fatigue | P value | No fatigue | Fatigue | P value | |
| n | 2225 | 623 | ||||
| Age (years) | 61.9±9.8 | 60.0±9.8 | <0.001 | – | – | |
| BMI (kg/m2) | 26.1±4.4 | 27.4±5.0 | <0.001 | – | – | |
| Handgrip (kg) | 35.0±12.0 | 33.8±12.0 | 0.022 | 35.0±0.2 | 35.3±0.3 | 0.430 |
| Ferritin (µg/L) | 149 (92–229) | 139 (83–214) | 0.034* | 188±4 | 185±8 | 0.732 |
| TSH (mUI/L) | 2.1 (1.5–3.0) | 2.1 (1.5–2.9) | 0.374* | 2.5±0.1 | 2.4±0.1 | 0.332 |
| Free T4 (pmol/L) | 16.2±2.5 | 16.3±2.6 | 0.190 | 16.2±0.1 | 16.4±0.1 | 0.221 |
Results are expressed as average ±SD or as median (IQR) for the bivariate analysis and as multivariable-adjusted average ±SE for the multivariable analysis. Bivariate analysis performed using Student’s t-test or Kruskal-Wallis non-parametric test (*).Multivariable analysis conducted using analysis of variance adjusting for gender, age group, BMI categories, insomnia categories, educational level, diabetes, presence of antihistame, antidepressant or hypnotic drugs, self-rated health, and depression.
BMI, body mass index; TSH, thyroid stimulating hormone.