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Inhibition of P-glycoprotein (transmembrane efflux pump belonging to the ATP binding cassette family) by silychristin derivatives: (a) silychristin A; (b) 2,3-dehydrosilychristin A; (c) isosilychristin; (d) anhydrosilychristin. Data are presented as the average of three measurements with corresponding standard error of the mean. The Ymax /Ymin values were as follows: (a) 100/44 ± 2; (b) 100/37 ± 2; (c) 100/0; (d) 100/0.
