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Effect of cigarette smoke (CS) on heme-oxygenase (HO-1) expression evaluated on human skin explants (HSE) treated with NLCT 10 or NLCT 10-TOC, exposed to air or CS for 30 min and harvested after 24 h. A) Representative Western blot analyses of HO-1 protein expression (with the respective β-actin controls). B) Mean expression of HO-1 as a ratio of β-actin. The results are shown as the mean of three experiments. * p < 0.05 with respect to the control.
