Table 4.
Dimensional characteristics of SLNs or NLCs and the presence of agglomerates.
| Preparation | Z-average, Dz (nm) | Polydispersity index | Agglomeratea (%) |
| SLN T5 | 148.6 ± 74.5 | 0.35 ± 0.11 | 2.86 ± 0.04 |
| SLN T10 | 164.9 ± 9.4 | 0.33 ± 0.04 | 4.65 ± 0.03 |
| SLN C5 | 244.5 ± 26.5 | 0.36 ± 0.01 | 3.43 ± 0.02 |
| SLN C10 | 488.9 ± 25.3 | 0.32 ± 0.04 | 3.77 ± 0.04 |
| SLN P5 | 245.5 ± 31.9 | 0.31 ± 0.03 | 2.48 ± 0.03 |
| SLN P10 | 453.1 ± 9.3 | 0.39 ± 0.02 | 2.99 ± 0.04 |
| SLN S5 | 220.9 ± 15.6 | 0.37 ± 0.06 | 1.13 ± 0.03 |
| SLN S10 | 201.8 ± 82.1 | 0.39 ± 0.06 | 0.60 ± 0.04 |
| NLC T5 | 122.6 ± 34.2 | 0.32 ± 0.07 | 2.14 ± 0.02 |
| NLC T10 | 127.9 ± 29.1 | 0.29 ± 0.03 | 2.54 ± 0.01 |
| NLC C5 | 160.2 ± 25.5 | 0.29 ± 0.03 | 3.15 ± 0.02 |
| NLC C10 | 136.8 ± 51.5 | 0.24 ± 0.04 | 3.25 ± 0.01 |
| NLC P5 | 148.1 ± 29.5 | 0.22 ± 0.10 | 1.51 ± 0.01 |
| NLC P10 | 159.8 ± 33.7 | 0.30 ± 0.08 | 1.84 ± 0.02 |
| NLC S5 | 131.3 ± 30.5 | 0.31 ± 0.05 | 0 ± 0.01 |
| NLC S10 | 136.1 ± 13.5 | 0.29 ± 0.07 | 0 ± 0.01 |
aLoss of lipids (lipid phase) due to the partial coalescence of the lipid phase during the formation of the O/W emulsion. % refers to the weight of the lipid phase. Data represent the mean ± SD of 6 independent experiments.