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The Raman signals of exosomes were enhanced by Au nanoparticles. (a) The SERS and non-SERS spectra of exosomes; (b) Plasmon resonance absorption of Au colloid and exosomes; (c) The particle size distribution of Au colloid by DLS; (d) TEM of AuNPs; (e) TEM of gold nanoparticles and exosomes complex; (f) Mean SERS spectra (black line) and the standard deviation (gray area) of EC109 cell-derived exosome.
