Table 3.
Comparison of two CKD-specific symptom questionnaires based on feedback of the patient panel (n = 151)
| DSI (n = 76) | IPOS-Renal (n = 75) | p-value | |
|---|---|---|---|
| Age (years) | 60.6 (12.5) | 60.2 (10.4) | 0.8 |
| Treatment modality | 0.5 | ||
| Pre-dialysis | 6 (7.9) | 13 (17.3) | |
| Haemodialysis | 8 (10.5) | 9 (12.0) | |
| Peritoneal dialysis | 6 (7.9) | 4 (5.3) | |
| Transplant | 53 (69.7) | 47 (62.7) | |
| Other | 3 (3.9) | 2 (2.7) | |
| Objective time to complete* (minutes) | 5.4 (1.6) | 7.5 (1.8) | < 0.001 |
| Subjective time to complete* (minutes) | 3.2 (1.8) | 4.8 (1.6) | < 0.001 |
| Number of symptoms reported^ | 12.0 (6.5) | 8.0 (4.1) | < 0.001 |
| Additional 1–3 symptoms reported# | 21 (27.6) | 25 (33.3) | 0.5 |
| Burdensome of questionnaire (yes) | 4 (5.3) | 2 (2.7) | 0.4 |
| Appropriate frequency of submission (times per year) | 2.7 (1.8) | 2.9 (2.2) | 0.6 |
Values are shown in n (%) or mean (SD)
The DSI and IPOS-Renal questionnaires showed good reliability for symptom burden score with Cronbach’s alpha values of 0.90 and 0.86, respectively
*Objective time to complete was defined as the difference in minutes between the start and completion of the online questionnaire. Subjective time to complete is the time to complete estimated by the patient. Values shown as geometric mean (SD)
^The number of symptoms reported is based on the symptoms defined in the questionnaire and rated by the patient as bothering a little bit to very much (or affecting slightly to overwhelmingly)
#The number of patients reporting an additional 1 to 3 symptoms not mentioned in de questionnaire
Abbreviations: CKD, Chronic Kidney Disease; DSI, Dialysis Symptom Index; IPOS-Renal, Palliative Care Outcome Scale - Renal Version