Table 4.

Diagnostic Odds Ratios* for individual clinical presentations stratified by age group (<60, 60 to 69, ≥70 years) that showed evidence of effect modification

Symptom	Diagnostic ORs			P value for effect modification
	Age group (years)
	<60	60–69	≥70
Anxiety	1.44	1.39	1.24	0.02
Ataxia	8.28	9.57	5.16	0.004
Confusion	43.9	96.4	12.6	<0.001
Consciousness	6.93	7.03	3.1	0.02
Depression	1.5	2.65	2.77	<0.001
Headache	11.3	9.15	6.08	<0.001
Nausea	6.86	5.82	3.19	<0.001
Seizure	89.3	70	14.5	<0.001
Sleep	2.72	1.48	1.78	0.03
Visual	22.8	5.11	4.9	<0.001

*Models adjusted for age group, gender and Charlson Comorbidity Index.