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. 2019 Aug 12;9(8):546. doi: 10.3390/ani9080546

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The protein–protein interaction networks of the DAPs were built using STRING 10.5 with a combined score larger than 0.7 (high confidence) and visualized with Cytoscape 3.4.0. DAPs are represented by round nodes. The pink node indicates up-regulation and the green node indicates down-regulation of the DAPs. The node size indicates high interaction degree (large) or low interaction degree (small). Proteins are connected with each other by an edge, which color indicates the combined score.