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Synthetic route of target compounds 10a-j from the intermediate 3. (a) Substituted phenylhydrazine hydrochloride, EtOH, conc. HCl, reflux, 3 h; (b) 1,2-dibromoethane, TBAB, NaOH, benzene, H2O, rt, 12 h; (c) piperazine, K2CO3, KI, MeCN, reflux, 8 ∼ 12 h.
