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. 2019 Aug 30;9(8):e030252. doi: 10.1136/bmjopen-2019-030252

Table 3.

Association between smoking and in-hospital mortality according to baseline characteristics

Baseline characteristics Current smoker Ex-smoker Non-smoker Pinteraction value
Age≥55 years 0.78 (0.69 to 0.89) 0.90 (0.77 to 1.05) Reference 0.0986
Age<55 years 0.72 (0.53 to 0.99) 0.85 (0.48 to 1.49) Reference
Male 0.78 (0.68 to 0.89) 0.94 (0.80 to 1.10) Reference 0.0163
Female 0.75 (0.58 to 0.98) 0.45 (0.26 to 0.77) Reference
BMI≥24 kg/m2 0.80 (0.67 to 0.94) 0.89 (0.71 to 1.12) Reference 0.2063
BMI<24 kg/m2 0.74 (0.63 to 0.88) 0.89 (0.73 to 1.10) Reference
LVEF≥50% 0.77 (0.67 to 0.88) 0.98 (0.82 to 1.16) Reference 0.0149
LVEF<50% 0.87 (0.68 to 1.11) 0.74 (0.54 to 1.01) Reference
Hypertension—Yes 0.85 (0.72 to 1.00) 0.96 (0.78 to 1.17) Reference 0.4556
Hypertension—No 0.70 (0.59 to 0.83) 0.80 (0.64 to 1.01) Reference
Previous angina—Yes 0.84 (0.65 to 1.07) 0.83 (0.62 to 1.12) Reference 0.1833
Previous angina—No 0.76 (0.66 to 0.87) 0.92 (0.78 to 1.10) Reference
Previous MI—Yes 0.67 (0.47 to 0.97) 0.67 (0.45 to 1.00) Reference 0.0557
Previous MI—No 0.77 (0.68 to 0.87) 0.91 (0.78 to 1.07) Reference
Previous PCI—Yes 0.95 (0.44 to 2.04) 1.23 (0.56 to 2.72) Reference 0.7975
Previous PCI—No 0.78 (0.69 to 0.88) 0.89 (0.76 to 1.04) Reference
Previous HF—Yes 0.96 (0.57 to 1.60) 0.85 (0.53 to 1.37) Reference 0.0086
Previous HF—No 0.77 (0.68 to 0.87) 0.88 (0.76 to 1.03) Reference
Diabetes—Yes 0.78 (0.60 to 1.02) 0.86 (0.63 to 1.18) Reference 0.4065
Diabetes—No 0.77 (0.67 to 0.88) 0.90 (0.76 to 1.07) Reference
Hyperlipidaemia—Yes 0.75 (0.45 to 1.24) 1.16 (0.66 to 2.03) Reference 0.1239
Hyperlipidaemia—No 0.77 (0.68 to 0.87) 0.87 (0.74 to 1.02) Reference
Diagnosis of STEMI 0.81 (0.71 to 0.93) 0.93 (0.78 to 1.11) Reference 0.9700
Diagnosis of NSTEMI 0.61 (0.48 to 0.78) 0.71 (0.54 to 0.92) Reference

Adjusted for age, gender, BMI, systolic blood pressure, heart rate, admission diagnosis, cardiac arrest, chest pain, ST elevation, anterior wall MI, Killip classification, risk factor (medical history of diabetes, hypertension, hyperlipidaemia, premature family CAD history, heart failure, renal failure and COPD), medical history (previous angina, PCI and CABG), creatinine level, haemoglobin level, GRACE risk score and primary PCI.

BMI, body mass index;CABG, coronary artery bypass grafting; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; GRACE, Global Registry of Acute Coronary Events; HF, heart failure; LVEF, left ventricular ejection fraction; MI, myocardial infarction;NSTEMI, non-ST-elevation MI; PCI, percutaneous coronary intervention; STEMI, ST-elevation MI.