Table 2.
Differential identified metabolites for discrimination among control and BA-12 groups based on GC–MS metabolomics. RT—retention time; VIP—variable importance for projection; MEOX—methoxime; TMS—trimethylsilyl.
| RT (min) | Actual m/z | Metabolite | m/z | Formula | Derivative Type | Derivative Weight/Formula | Predicted m/z | VIP | p (corr) |
|---|---|---|---|---|---|---|---|---|---|
| 3.38 | 236.5340 | Chalcone (HMDB0003066) | 208.2552 | C15H12O | 1 MEOX | C16H15NO | 237.1154 | 1.38 | 0.90 |
| 5.53 | 234.4430 | Melatonin (HMDB0001389) | 232.2783 | C13H16N2O2 | Underivatized | 1.16 | 0.65 | ||
| 16.70 | 340.5060 | 5-Methylcytosine (HMDB0002894) | 125.1286 | C5H7N3O | 3 TMS | C14H31N3OSi3 | 341.6720 | 9.19 | 0.98 |
| 19.80 | 86.1770 | Putrescine (HMDB0001414) | 88.1515 | C4H12N2 | Underivatized | 4.42 | −0.52 |
The significant differences were generated from a Student’s t-test or Mann–Whitney U test when the Student’s t-test was not suitable.