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. 2019 Aug 7;8(8):288. doi: 10.3390/antiox8080288

Figure 3.

Figure 3

(A) The effects of aging, surgical castration, and testosterone replacement therapy on the ratio of the reduced/oxidized glutathione content (GSH + GSSG; expressed as nmol/mg protein). The results are shown as the means ± S.E.M. n = 8–9. (B) The effects of aging, surgical castration, and testosterone replacement therapy on the cardiac cyclic guanosine monophosphate level (cGMP; expressed as nmol/mg protein). The results are shown as the means ± S.E.M. n = 8–9. * p < 0.05: Statistical significance relative to the Young/SO fertile group, # p < 0.05: Statistical significance between age-matched CAS and CAS + T groups, CAS = surgical castration, T = testosterone replacement therapy, Cypr = cyproterone acetate treatment, and SO = sham operation.