Table 2.
Changes in the serum levels of testosterone (expressed as: ng/dL), glutamic oxaloacetic transaminase (GOT: expressed as U/L), glutamic-pyruvic transaminase (GPT: expressed as (U/L), cholesterol (expressed as mmol/L), and triglyceride (expressed as mmol/L). The results are shown as the means ± S.E.M. n = 4–10. * p < 0.05: Statistical significance relative to the Young/SO fertile group, # p < 0.05: Statistical significance between age-matched CAS and CAS + T groups, CAS = surgical castration, T = testosterone replacement therapy, Cypr = cyproterone acetate treatment, and SO = sham operation.
| Young | Aging | |||||||
|---|---|---|---|---|---|---|---|---|
| Fertile | CAS | CSA + Cypr | CAS + T | SO | CAS | CAS + Cypr | CAS + T | |
| Testosterone (ng/dl) | 237.40 ± 36.58 | 0 ± 0 * | 0 ± 0 * | 149.86 ± 21.19 # | 95.90 ± 12.26 * | 0 ± 0 * | 0 ± 0 * | 364.50 ± 50.19 *,# |
| GOT (U/l) | 94.57 ± 3.02 | 106.67 ± 11.85 | 142.50 ± 23.50 | 105.14 ± 3.91 | 184.75 ± 18.72 * | 163.86 ± 6.11 * | 163.00 ± 10.64 * | 145.29 ± 13.03 |
| GPT (U/l) | 56.00 ± 1.60 | 5.00 ± 1.22 | 77.00 ± 6.23 | 59.57 ± 1.85 | 94.00 ± 10.10 * | 88.25 ± 3.66 * | 90.67 ± 6.38 * | 79.13 ± 5.11 |
| Cholesterol (mmol/l) | 2.20 ± 0.13 | 2.78 ± 0.13 | 3.09 ± 0.12 | 2.29 ± 0.08 | 3.86 ± 0.44 | 4.65 ± 0.63 * | 4.81 ± 0.86 * | 4.46 ± 0.51 * |
| Triglyceride (mmol/l) | 0.92 ± 0.13 | 1.01 ± 0.06 | 2.84 ± 0.39 * | 1.28 ± 0.13 | 1.62 ± 0.31 | 1.69 ± 0.27 | 1.75 ± 0.30 | 1.33 ± 0.15 |