Table 1.

Enriched GO terms and KEGG pathways of DEGs in the proliferation stage

Proliferation stage	GO enrichment	Gene count	Log (q-value)	KEGG pathway	Gene count	Log (q-value)
Up at -48 h	mRNA catabolic process	44	− 23.15	Ribosome	30	−22.09
	Mitotic cell cycle phase transition	45	−16.92	PI3K-Akt signaling pathway	23	−6.36
	Ribosomal subunit	34	−22.87	Cell cycle	20	−12.60
	RNA splicing	29	−8.00	Spliceosome	14	−6.20
	Focal adhesion	26	−7.40	DNA replication	14	−3.14
	Cholesterol biosynthetic process	16	−11.48	Glycolysis	6	−4.953
Up at 0 h	Actin cytoskeleton organization	44	−12.86	Focal adhesion	22	−9.80
	Calcium ion binding	42	−10.43	ECM-receptor interaction	17	−11.44
	Cadherin binding	29	−11.76	Regulation of actin cytoskeleton	12	−2.33
	Focal adhesion	25	−5.88	Calcium signaling pathway	11	−2.24
	Collagen fibril organization	13	−9.30	MAPK signaling pathway	10	−0.86