Table 1.
Study formulas.
| Characteristics | Study Formula * | |
|---|---|---|
| IPF | EHF | |
| Nutrient density (cal/fl oz) | 24 | 24 |
| Nutrient composition per 100 kcal | ||
| Total Protein (g, % calories) † | 3.0, 12% | 2.8, 11% |
| Total Carbohydrate (g, % calories) ‡ | 11, 44% | 10.2, 41% |
| Total Fat (g, % calories) § | 5.1, 44% | 5.6, 48% |
| Arachidonic acid (ARA), mg | 34 | 34 |
| Docosahexaenoic acid (DHA), mg | 17 | 17 |
| Potential Renal Solute Load (mOsm/100 Cal) | 27 | 25 |
| Potential Renal Solute Load (mOsm/100 mL) | 21 | 21 |
| Osmolality (mOsm/kg H2O) | 310 | 340 |
| Osmolarity (mOsm/L) | 270 | 300 |
* Marketed study formulas (Mead Johnson Nutrition, Evansville, IN, USA) included intact cow milk protein preterm formula (IPF: Enfamil® Preterm) and extensively hydrolyzed cow milk protein formula (EHF: Pregestimil®). † Sources of protein, IPF: skim milk and whey protein concentrate; EHF: casein hydrolysate, l-cystine, l-tyrosine, l-tryptophan. ‡ Sources of carbohydrate, IPF: glucose polymers and lactose; EHF: corn syrup solids and modified corn starch. § Sources of fat: medium-chain triglyceride (MCT) oil (38%, IPF; 53%, EHF), soybean oil, high oleic sunflower oil, coconut oil (IPF only), lecithin, and ascorbyl palmitate; ARA and DHA from single-cell oils.