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Cytotoxicity of C18-EdV in ARPE19 cells. The cells were treated with increasing concentrations of EdV, C18-edaravone for 24 h (A) and 48 h (B) in complete culture medium. The viability of treated-cells is reported as percentage respect with no-treated cells, which are considered as 100% of cell viability. The values in the figures are expressed as the means ± SD. Differences between control vs. C18-EdV or EdV were assessed using Tukey’s post hoc test, * p < 0.0001.
