Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 2;16:23. doi: 10.1186/s12979-019-0162-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — AuNP-M2e + sCpG induces long-term M2e-specific antibody titer. (a) A cohort of mice were vaccinated 0, 2, or 3 times with AuNP-M2e + sCpG vaccine and bleed at week 69.5. Diagram shows experimental design. (b) Antibody titer determined by ELISA. M2e peptide was used as the coating antigen for ELISAs. Serum from specified mice and time point was added. M2e-specific titer was detected by an IgG subclass specific secondary antibody. Average background from naïve unvaccinated serum was subtracted out. OD 490 nm = Optical Density 490 nm. n = 18–19, One-way ANOVA with Tukey’s multiple comparison test. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001