Table 1.
Ages of mice at experimental time points
| Group | # of Mice | Age (months) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| AuNP-M2e-CpG 1 | AuNP-M2e-CpG 2 | AuNP-M2e-CpG 3 | Bleed 2 | Bleed 3 | Bleed 4 | H1N1 Infection | Bleed 5 | ||
| Bleed 1 | |||||||||
| X3 (1)* | 9 | 3.4 | 4.1 | 4.9 | 5.5 | 5.8 | 20.6 | 20.8 | 23.8 |
| X3 (2)* | 10 | 0.8 | 1.5 | 2.3 | 2.9 | 3.3 | 18.1 | 18.2 | 21.3 |
| X2 | 19 | 0.8 | 1.5 | – | – | – | 18.1 | 18.2 | 21.3 |
| Naïve | 19 | – | – | – | – | – | 10.6 | 10.7 | 13.8 |
| Experimental Time Point (weeks): | 0 | 3 | 6 | 7.5 | 9 | 69.5 | 70 | 83 | |
Mice were specified age in months at given time points (listed in weeks in bold). Mice over the age of 18 months are considered geriatric age (shown in italics). Groups that were not manipulated at a given time point have a dashed line ----. *3X Groups (1) and (2) were combined for all analysis as there was no significant difference between their antibody titer at any time point or their survival. (Data shown in Fig. 4g)