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. 2019 Aug 12;24(16):2919. doi: 10.3390/molecules24162919

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Dynamics and PRE data on RL2 and MTSL-RL2. Error bars represent random noise error of fitting the experimental data. (A) A comparison of T₁ values of RL2 at pH 3.5 (blue) and diamagnetic MTSL-RL2 (orange). (B) The comparison of T₂-values of RL2 at pH 3.5 (blue) and diamagnetic MTSL-RL2 (orange). (C) A comparison of hetero NOE values of RL2 at pH 3.5 (blue) and diamagnetic MTSL-RL2 (orange). (D) Integral ratios of peaks in the HSQC paramagnetic and diamagnetic spectra of MTSL-RL2. The blue dashed curve is a three-point moving window average for the best trend view. The asterisk indicates the MTSL-label site (Cys8).