Figure 4.

Predicted directional interactions of TFs and the co-expressed modules in the sesame CARGs. Network plots of inferred connections between TF and genes in the three modules. The promoter sequences of genes associated with each module were tested for overrepresentation of DNA motifs shown to be bound to TFs that are differentially transcribed following stress treatments. Each TF with a known motif is represented by a colored circle corresponding to its appertaining module. The different modules are represented by a rectangle. An edge between a TF and a module indicates significant enrichment of the corresponding binding motif in that module. The size of each TF node is proportional to the number of predicted regulated downstream genes. Logos of the seven enriched DNA binding motifs within the promoter regions of the genes belonging to each module detected by WGCNA were added.