Table 21.
The cytostatic activities of the cytosine (49a) and 5-azacytosine (49b) ASA derivatives.
| Comp. | IC50 (μM) | |||||
|---|---|---|---|---|---|---|
| HeLa | MCF-7 | HepG2 | SW 620 | MiaPaCa-2 | WI 38 | |
| 49a | 7.20 | 2.03 | 1.98 | >100 | 24.24 | 8.49 |
| 49b | 5.91 | 3.49 | 2.72 | 5.62 | 0.92 | 4.67 |
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