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The cytostatic activities of 9-deazapurine ASA derivatives.
| Comp. | IC50 (μM) | ||||||
|---|---|---|---|---|---|---|---|
| L1210/0 | CEM/0 | HeLa | MiaPaCa-2 | Hep-G2 | SW620 | 3T3 | |
| 57 | 4.7 | 4.1 | 12 | 33.9 | >100 | 47.1 | >100 |
| (Z, Z)-59 | 4.5 | 19 | 5.6 | 26.2 | >100 | 47.2 | >100 |
| 5-FU | NT a | NT a | 66.5 | 11.67 | 55.2 | 0.79 | 28.3 |
a NT = not tested.
