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The criteria of histological scores.
| Features | Scores | Description |
|---|---|---|
| Epithelium | 0 | Normal morphology |
| 1 | Loss of goblet cells | |
| 2 | Loss of goblet cells in large areas | |
| 3 | Loss of crypts | |
| 4 | Loss of crypts in large areas | |
|
| ||
| Infiltration | 0 | No infiltration |
| 1 | Infiltration around crypt bases | |
| 2 | Infiltration reaching the muscularis mucosa | |
| 3 | Extensive infiltration reaching the muscularis mucosa and thickening of the mucosa with abundant edema | |
| 4 | Infiltration of the submucosa | |
