Table 2.
Characteristics of pregnant women with incident or prevalent depression during pregnancy or up to 6 months after the end of pregnancy of pregnancy who did and did not develop treatment resistant depression
| Characteristic | Pregnant women with depression but not TRD (n = 74,835) |
Pregnant women with TRD (n = 4354) |
P value | ||
|---|---|---|---|---|---|
| Age, years (mean, sd) | 31.0 | 6.1 | 30.5 | 6.3 | < 0.0001 |
| Age group, years (n, % | |||||
| 12–24 | 11,383 | 15.2% | 780 | 17.9% | < 0.0001 |
| 25–34 | 42,113 | 56.3% | 2387 | 54.8% | |
| 35–44 | 20,647 | 27.6% | 1141 | 26.2% | |
| 45–56 | 692 | 0.9% | 46 | 1.1% | |
| Deyo-Charlson severity index (mean, sd) | 0.33 | 1.01 | 0.38 | 1.02 | 0.002 |
| Comorbidities in prior year (n, %) | |||||
| Fatigue | 527 | 0.7% | 40 | 0.9% | 0.115 |
| Opioid dependence | 427 | 0.6% | 67 | 1.5% | < 0.0001 |
| Drug abuse | 371 | 0.5% | 40 | 0.9% | < 0.0001 |
| Tobacco dependence syndrome | 2460 | 3.3% | 200 | 4.6% | < 0.0001 |
| Anxiety disorder | 17,630 | 23.6% | 1483 | 34.1% | < 0.0001 |
| Obsessive-compulsive disorder | 672 | 0.9% | 87 | 2.0% | < 0.0001 |
| Social phobia | 127 | 0.2% | 10 | 0.2% | 0.345 |
| Eating disorder | 471 | 0.6% | 42 | 1.0% | 0.011 |
| Insomnia | 2192 | 2.9% | 294 | 6.8% | < 0.0001 |
| Pain of head and neck | 14,504 | 19.4% | 1107 | 25.4% | < 0.0001 |
| Musculoskeletal pain | 9354 | 12.5% | 660 | 15.2% | < 0.0001 |