. 2019 Jul 30;11(8):1082. doi: 10.3390/cancers11081082

Table 2.

Identification of tumor-associated DC subsets by flow cytometry.

Histology	Markers	DC Subset	Maturation State	Reference
Breast cancer	Lin⁻ CD4⁺ CD11c⁻ CD123⁺ BDCA2⁺	pDC	Mature	[44]
Breast cancer	Lin⁻ CD4⁺ CD11c⁺ BDCA1⁺	cDC2	NA	[44]
Colorectal cancer	HLA-DR⁺ CD11c⁺ IRF8⁺	cDC1	NA	[80]
	HLA-DR⁺ CD11c⁺ BDCA1⁺	cDC2	NA
	HLA-DR⁺ CD11c⁺ CD14⁺	MoDC	NA
Lung cancer	CD1c⁺	cDC2/LC	NA	[145]
	CD123⁺ BDCA2⁺	pDC	NA	[145]
	HLA-DR⁺ CD11c⁺ IRF8⁺	cDC1	NA	[80]
	HLA-DR⁺ CD11c⁺ BDCA1⁺	cDC2	NA
	HLA-DR⁺ CD11c⁺ CD14⁺	MoDC	NA
Melanoma	HLA-DR⁺ BDCA2⁺	pDC	NA	[146]
	HLA-DR⁺ CD11c⁺ BDCA3⁺	cDC1	NA	[77]
	HLA-DR⁺ CD11c⁺ BDCA1⁺	cDC2	NA	[77]
Ovarian cancer	Lin⁻ CD4⁺ CD11c⁻	pDC	Immature	[147]
	HLA-DR⁺ CD4⁺ CD123⁺ CD11c⁻	pDC	Immature	[148]
	Lin- CD4⁺ CD11c⁻ CD123⁺ BDCA2⁺	pDC	Mature	[142]
	Lin⁻ CD4⁺ CD11c⁺	cDC	NA	[142]

DC: Dendritic Cells; LC: langerhans cells; cDC1: conventional dendritic cell type 1; cDC2: conventional dendritic cell type 2; pDC: plasmacytoid dendritic cells; MoDC: monocytes-derived dendritic cells; mDC: myeloid dendritic cells; NA: not available.