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. 2019 Jul 26;9(8):177. doi: 10.3390/brainsci9080177

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Experimental protocol. The conditioning stimulus (CS) coil was applied to the dorsolateral prefrontal cortex (DLPFC) and the test stimulus (TS) coil was applied to primary motor cortex (M1) in the left (Experiments 1 and 2) and right hemispheres (Experiments 3 and 4). DLPFC-ipsilateral M1 interactions were probed while participants were at rest or maintaining a 20% maximum voluntary contraction (MVC) of the left and right first dorsal interosseous (FDI) muscles. The CS intensity was 80% or 120% of resting motor threshold (RMT). The interstimulus interval (ISI) between pulses were 4, 5, 6, 7, 8, 9, 10, 11, 12, 15 or 20 ms.