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. 2019 Sep 2;18:168. doi: 10.1186/s12944-019-1103-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Effect of 4-cholesten-3-one on cell viability after LXRα and LXRβ knockdown. Cells were transfected or not with a siRNA specific for LXRα and LXRβ (20 nM) or a siRNA control. After 48 h of incubation, the cells were treated or not with 4-cholesten-3-one at the concentrations indicated. (a) LXRα and LXRβ relative mRNA expression determined by RT-qPCR after 48 h of transfection time. (b) Cell viability of MCF-7 and MDA-MB-231 cells after transfection and treatment with 4-cholesten-3-one. All data were presented as mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001. ns means not significant