Table 2.
KEGG pathway analysis of differentially expressed genes associated with hepatocellular carcinoma.
| Category | Term | Count | % | P value | Genes |
|---|---|---|---|---|---|
| Up regulated | ssc05219: bladder cancer | 4 | 0.02 | 0.002 | VEGFA, CXCL8, HBEGF, THBS1 |
| ssc05323: rheumatoid arthritis | 5 | 0.03 | 0.002 | JUN, IFNG, VEGFA, CXCL8, ITGB2 | |
| ssc05144: malaria | 4 | 0.02 | 0.004 | IFNG, CXCL8, ITGB2, THBS1 | |
| ssc05168: herpes simplex infection | 5 | 0.03 | 0.024 | SRSF3, JUN, IFNG, CYCS, CUL1 | |
| ssc04380: osteoclast differentiation | 4 | 0.02 | 0.047 | FOSL2, SQSTM1, JUN, IFNG | |
|
| |||||
| Down regulated | hsa05162: measles | 8 | 0.05 | <0.001 | CCNE2, TNFSF10, EIF2S1, TLR4, HSPA1A, HSPA1B, MSN, TLR7 |
| hsa05164: influenza A | 8 | 0.05 | 0.001 | TNFSF10, EIF2S1, TLR4, HSPA1A, HSPA1B, TLR7, HLA-DQA1, HLA-DRA | |
| hsa05323: rheumatoid arthritis | 6 | 0.04 | 0.001 | CXCL5, TLR4, LTB, HLA-DQA1, HLA-DRA, IL11 | |
| hsa04612: antigen processing and presentation | 5 | 0.03 | 0.004 | HSPA1A, HSPA1B, KLRD1, HLA-DQA1, HLA-DRA | |
| hsa05134: legionellosis | 4 | 0.03 | 0.012 | NLRC4, TLR4, HSPA1A, HSPA1B | |