Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jul 28;11(8):1066. doi: 10.3390/cancers11081066

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Reduced condensin gene expression induces aberrant numerical and decompaction phenotypes in HCT116. (A) Bar graph presenting the frequency of enumerable and chromosome decompaction phenotypes (severe and mild) following gene silencing. (B) Dot plot depicting an overall increase in chromosome number heterogeneity following condensin gene silencing relative to siControl. The horizontal line identifies the modal chromosome number of HCT116. KS tests reveal statistically significant differences in the cumulative distribution frequencies of chromosome numbers relative to siControl (***, p < 0.001; ****, p < 0.0001). (C) Bar graph depicting overall increases in the frequency of aberrant chromosome numbers following condensin gene silencing.