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. 2019 Jul 27;11(8):1064. doi: 10.3390/cancers11081064

Figure 3.

Figure 3

Diagnostic accuracy of the tCEC test for detection of clinically significant cancer in men with PSA readings <10 ng/mL on TRUS biopsy. tCEC: tumour-associated circulating endothelial cells, TRUS biopsy: transrectal ultrasound-guided biopsy. Primary definition: Sensitivity 75% (95% confidence interval (CI) 43–95), specificity 67% (53–79), positive predictive value 32% (16–52), negative predictive value 93% (80–98). Secondary definition: Sensitivity 71% (29–96), specificity 63% (50–75), positive predictive value 18% (6–37), negative predictive value 95% (83–99).