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. 2019 Aug 2;11(8):1102. doi: 10.3390/cancers11081102

Table 3.

Correlation between mRNA expression levels of various NFkB pathway molecules with mRNA expression markers of different types of infiltrating immune cells. r = two-tailed Spearman correlation coefficient. p ≤ 0.05 is considered significant. Bonferroni correction was applied.

Markers CD3E CD3D1 CD4 CD8A CD68 CD163
r p r p r p r p r p r p
NFkB1 0.398 0.01 0.298 0.17 0.227 0.71 0.365 0.03 0.172 1 0.009 1
NFkB2, pr1 0.378 0.02 0.213 0.91 0.195 1 0.258 0.39 0.375 0.02 −0.086 1
NFkB2, pr2 0.361 0.03 0.242 0.54 0.278 0.26 0.267 0.33 0.411 0.01 0.040 1
RELA 0.110 1 −0.095 1 −0.119 1 −0.125 1 −0.062 1 −0.065 1
RELB 0.363 0.03 0.365 0.03 0.308 0.13 0.327 0.08 0.149 1 0.317 0.11
SPP1, pr1 −0.295 0.18 −0.247 0.49 −0.337 0.06 −0.280 0.25 −0.442 0.001 −0.265 0.35
SPP1, pr2 −0.297 0.17 −0.251 0.46 −0.330 0.08 −0.281 0.25 −0.447 0.001 −0.243 0.53
PPARγ, pr1 −0.174 1 −0.327 0.08 −0.475 0.001 −0.256 0.41 −0.221 0.79 −0.399 0.01
PPARγ, pr2 −0.195 1 −0.311 0.12 −0.460 0.001 −0.276 0.27 −0.209 0.97 −0.353 0.04
IkBkG 0.184 1 0.196 1 0.233 0.64 0.188 1 −0.009 1 0.354 0.04